HDL Exposing the complexity

I had a physician argue that his diabetes patient with an HDL of 70 was safe from cardiovascular risks. He of course did know of the inner complexities of the HDL. I explained to him that in diabetes patients, a HDL may actually to proatherogenic. HDL functions by promoting cholesterol efflux and inhibiting inflammation. But, if the HDL is overloaded, such as the patient with the HDL of 70, it can actually be pro-inflammatory.

A good editorial to read....