A study in the journal Diabetes examined the role of butyric acid, a short-chain fatty acid formed by fermentation in the large intestine, in the regulation of insulin sensitivity in mice fed a high-fat diet.
The concluded that:
Dietary supplementation of butyrate can prevent and treat diet-induced insulin resistance in mouse.
The mechanism of butyrate action is related to promotion of energy expenditure and induction of mitochondria function.
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