Monday, November 2, 2009

Sulfonylureas Tied to Higher Mortality After MI

The following are article was in the internal medicine news this month.  It showed an increased risk of MI in patients with sulfonureas.

"BARCELONA — Four widely prescribed oral sulfonylurea drugs are associated with significantly increased risk of all-cause mortality compared with metformin in type 2 diabetic patients with a history of MI, according to a comprehensive Danish national cohort study.

The study included all Danish adults with a prior MI who started on oral glucose-lowering monotherapy during 1997-2006. The conclusion: Glimepiride, glyburide, glipizide, and tolbutamide were associated with 33%-43% higher mortality risk than was metformin, Dr. Tina Ken Schramm said at the annual congress of the European Society of Cardiology."

Click here to read further.

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