Tuesday, May 4, 2010

Androgen abuse in athletes

Shehzad Basaria

J Clin Endocrinol Metab 2010 95: 1533-1543

I liked this article for several reasons:

1. Interesting and timely topic. Not only as it relates to professional sports, but also office consultations from non-professional athletes who have gotten involved in performance enhancement, knowingly or unknowingly through "supplements".

2. Nice mini-review of androgen synthesis and degradation and how this relates to detection

3. Interesting biochemistry for the assays. I love the genetic engineering of yeast to contain androgen receptors which can then activate the firefly gene luciferase to glow in the presence of androgen. See figure 4 for that.

Naturally you can check out the article as a pdf at Google docs through goodreader. By the way I downloaded Apple's Pages and am looking into a keyboard for the iPad now. This article comparing keyboards was helpful.

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