Thursday, November 15, 2012

Changes in CVD risk post-parathyroidectomy in PHPT

Effects of successful parathyroidectomy on metabolic cardiovascular risk factors in patients with severe primary hyperparathyroidism. 
Ishay A, Herer P, Luboshitzky R.

[Endocrine Practice, 2011, Ishay, parathyroidectomy, DBP, CVD]

- study to evaluate effect of parathyroidectomy on metabolic abnormalities associated with CVD

- 34 Pt with HPT and 40 control patients with normal calcium assessed at baseline and 1 year later. HPT patients had parathyroidectomy

- significant decrease in DBP and insulin. significant increase in spine BMD

- no significant change in metabolic syndrome rate, insulin resistance, or likelihood of CVD risk

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